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by law, which, however, could never be understood until the facts
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had been accumulated, tabulated and systematized. By his example,
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by his prodigious industry, and by his suggestive experiments he
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led men again into the old paths of Aristotle, Galen and Harvey.
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He made all thinking physicians naturalists, and he lent a
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dignity to the study of organic life, and re-established a close
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union between medicine and the natural sciences. Both in Britain
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and Greater Britain, he laid the foundation of the great
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collections and museums, particularly those connected with the
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medical schools. The Wistar-Horner and the Warren Museums in this
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country originated with men greatly influenced by Hunter. He
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was, moreover, the intellectual father of that interesting group
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of men on this side of the Atlantic who, while practising as
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physicians, devoted much time and labor to the study of natural
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history; such men as Benjamin Smith Barton, David Hossack, Jacob
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Bigelow, Richard Harlan, John D. Godman, Samuel George Morton,
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John Collins Warren, Samuel L. Mitchill and J. Ailken Meigs. He
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gave an immense impetus in Great Britain to the study of morbid
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anatomy, and his nephew, Matthew Baillie, published the first
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important book on the subject in the English language.
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Before the eighteenth century closed practical medicine had made
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great advance. Smallpox, though not one of the great scourges
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like plague or cholera, was a prevalent and much dreaded disease,
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and in civilized countries few reached adult life without an
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attack. Edward Jenner, a practitioner in Gloucestershire, and the
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pupil to whom John Hunter gave the famous advice: "Don't think,
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try!" had noticed that milkmaids who had been infected with
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cowpox from the udder of the cow were insusceptible to smallpox.
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I show you here the hand of Sarah Nelmes with cowpox, 1796. A
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vague notion had prevailed among the dairies from time immemorial
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that this disease was a preventive of the smallpox. Jenner put
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the matter to the test of experiment. Let me quote here his own
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words: "The first experiment was made upon a lad of the name of
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Phipps, in whose arm a little vaccine virus was inserted, taken
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from the hand of a young woman who had been accidentally infected
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by a cow. Notwithstanding the resemblance which the pustule,
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thus excited on the boy's arm, bore to variolous inoculation, yet
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as the indisposition attending it was barely perceptible, I could
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scarcely persuade myself the patient was secure from the Small
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Pox. However, on his being inoculated some months afterwards, it
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proved that he was secure."[8] The results of his experiments
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were published in a famous small quarto volume in 1798.[*] From
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this date, smallpox has been under control. Thanks to Jenner, not
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a single person in this audience is pockmarked! A hundred and
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twenty-five years ago, the faces of more than half of you would
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have been scarred. We now know the principle upon which
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protection is secured: an active acquired immunity follows upon
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an attack of a disease of a similar nature. Smallpox and cowpox
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are closely allied and the substances formed in the blood by the
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one are resistant to the virus of the other. I do not see how any
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reasonable person can oppose vaccination or decry its benefits.
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I show you the mortality figures[9] of the Prussian Army and of
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the German Empire. A comparison with the statistics of the
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armies of other European countries in which revaccination is not
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so thoroughly carried out is most convincing of its efficacy.
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[8] Edward Jenner: The Origin of the Vaccine Inoculation,
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London, 1801.
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[*] Reprinted by Camac: Epoch-making Contributions to Medicine,
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etc., 1909.--Ed.
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[9] Jockmann: Pocken und Vaccinationlehre, 1913.
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The early years of the century saw the rise of modern clinical
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medicine in Paris. In the art of observation men had come to a
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standstill. I doubt very much whether Corvisart in 1800 was any
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more skilful in recognizing a case of pneumonia than was Aretaeus
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in the second century A. D. But disease had come to be more
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systematically studied; special clinics were organized, and
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teaching became much more thorough. Anyone who wishes to have a
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picture of the medical schools in Europe in the first few years
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